60. Dahiya, G; Abboud, K. A.; Aponick, A. “Tuning StackPhim Ligands: Applications in Enantioselective Borylation and Alkynylation” Synthesis 2022, ASAP. DOi
59. Liu, J.; Laguna, E. M.; Mangadan, A. R. K.; Kang, K.; Aponick, A. “The Enantioselective Intermolecular Seagusa Allylation” ACS Catal. 2021, 11, 14842 DOi
58. Mangadan, A. R. K.; Liu, J.; Aponick, A. “Enantioselective Lactonization by π-Acid-Catalyzed Allylic Substitution: A Complement to π-Allylmetal Chemistry” Angew. Chem. Int. Ed. 2021, 60, 22224. DOi
57. Dahiya, G.; Pappoppula, M.; Aponick, A. “Configuration sampling with five-membered atropsiomeric P,N- ligands” Angew. Chem. Int. Ed. 2021, 60, 19604. DOi
56. Manda, J. N.; Markovic, M.; Zimmermann, E. M.; Ben-Shabat, S.; Dahan, A.; Aponick, A. “Phospholipid Cyclosporine Prodrugs Targeted at Inflammatory Bowel Disease (IBD) Treatment: Design, Synthesis, and in Vitro Validation” ChemMedChem 2020, 15, 1639. DOi
55. Markovic, M.; Ben-Shabat, S.; Aponick, A.; Zimmermann, E. M.; Dahan, A.; "Lipids and Lipid-Processing Pathways in Drug Delivery and Therapeutics" Int. J. Mol. Sci. 2020, 21, 3248. DOi
54. Mishra, S.; Aponick, A. “Lactone Synthesis by Enantioselective Orthogonal Tandem Catalysis”
Angew. Chem., Int. Ed. 2019, 58, 9485. DOi
53. DeRatt L. G.; Pappoppula, M.; Aponick, A. “A Facile Enantioselective Alkynylation of Chromones”
Angew. Chem., Int. Ed. 2019, 58, 8416. DOi
52. Liu, J.; Mishra, S.; Aponick, A. “Enol Acetates: Versatile Substrates for the Enantioselective
Intermolecular Tsuji Allylation” J. Am. Chem. Soc. 2018, 140, 16152. DOi
51. Markovic, M.; Ben-Shabat, S.; Keinan, S.; Aponick, A; Zimmermann, E. M.; Dahan, A. “Lipid Prodrug
Approach for Improved Oral Drug Delivery and Therapy” Med. Res. Rev. 2018, 39, 579. DOi
50. Markovic, M.; Ben-Shabat, S.; Keinan, S.; Aponick, A; Zimmermann, E. M.; Dahan, A. “Prospects and
Challenges of Phospholipid-Based Prodrug” Pharmaceutics 2018, 10, 210. DOi
49. Liu, J.; Miotto, R. J.; Segard, J.; Erb, A. M.; Aponick, A. “Catalytic Dehydrative Lactonization of Allylic
Alcohols” Org. Lett. 2018, 20, 3034. DOi
48. Dahan, A.; Markovic, M.; Keinan, S.; Kurnikov, I.; Aponick, A.; Zimmermann, E.M.; Ben-Shabat, S.
"Computational modeling and in-vitro/in-silico correlation of phospholipid-based prodrugs for targeted
drug delivery in inflammatory bowel disease" J. Comput. Aided Mol. Des. 2017, 31, 1021. DOI
47. Dahan, A.; Markovic, M.; Epstein, S.; Cohen, N.; Zimmerman, E.; Aponick, A.; Ben-Shabat, S.
“Phospholipid-drug conjugates as a novel oral drug targeting approach for the treatment of inflammatory
bowel disease” Eur. J. Pharm. Sci. 2017, 108, 78. DOI
46. Mishra, S.; Liu, J.; Aponick, A. “Enantioselective Alkyne Conjugate Addition Enabled by Readily Tuned
Atropisomeric P,N-Ligands” J. Am. Chem. Soc. 2017, 139, 3352. DOI
-Highlighted in JACS Spotlight J. Am. Chem. Soc. 2017, 139, 3919.
-Highlighted in Synfacts: Synfacts 2017, 13, 0521.
45. Paioti, P.H.S.; Abboud, K. A.; Aponick, A. “Incorporation of Axial Chirality into Phosphino-Imidazoline
Ligands for Enantioselective Catalysis” ACS Catal., 2017, 7, 2133. DOI
-Highlighted in Synfacts: Synfacts 2017, 13, 0607.
44. Dahan, A.; Ben-Shabat, S.; Cohen, N.; Keinan, S.; Kurnikov, I.; Aponick, A.; Zimmerman,
E. M. “Phospholipid-based prodrugs for drug targeting in inflammatory bowel disease: Computational
optimization and in-vitro correlation” Current Topics in Medicinal Chemistry, 2016,16, 2543. DOI
43. Paioti, P.H.S.; Abboud, K. A.; Aponick, A. “Catalytic Enantioselective Synthesis of Amino Skipped
Diynes ”J. Am. Chem. Soc. 2016,138, 2150. DOI
42. Silva J. O.; Angnes, R. A.; Silva, V. H. M. ; Servilha, B. M.; Adeel, M.; Braga, A. A. C.; Aponick, A.;
Correia C. R. D. “Intermolecular Non-Covalent Hydroxy-Directed Enantioselective Heck
Desymmetrization of Cyclopentenol: Computationally-driven Synthesis of Highly Functionalized
cis-4-Aryl-Cyclopentenol Scaffolds”J. Org. Chem. 2016, 81, 2010. DOI
41. Goodwin, J. A.; Ballesteros C. F.; Aponick, A. “Diastereoselective Synthesis of Protected 1,3-Diols by
Catalytic Diol Relocation” Org. Lett. 2015, 17, 5574. DOI
40. Pappoppula, M.; Aponick, A. “Enantioselective Total Synthesis of (-)-Martinellic Acid”
Angew. Chem., Int. Ed. 2015, 54, 15827. DOI
39. Pappoppula, M.; Cardoso, F. S. P.; Garrett, B. O.; Aponick, A. “Enantioselective Cu-Catalyzed
Quinoline Alkynylation” Angew. Chem., Int. Ed. 2015, 54, 15202. DOI
-Highlighted in Synfacts: Synfacts 2016, 12, 63.
38. Butler, B.B., Jr.; Aponick, A.; Acortatarin A "Spiroketalization Methods and Synthesis. In Strategies
and Tactics In Organic Synthesis" Michael Harmata, Ed.; Elsevier: Amsterdam, 2015, 11, 1.DOI
37. Goodwin, J. A.; Aponick, A. “Regioselectivity in the Au-catalyzed hydration and hydroalkoxylation
of alkynes” Chem. Commun., 2015, 51, 8730. DOI
36. Butler, B. B.; Manda J. N.; Aponick, A. “Synthesis of the Spirastrellolide A, B/C Spiroketal: Enabling
Solutions for Problematic Au(I)-Catalyzed Spiroketalizations” Org. Lett., 2015, 17, 1902. DOI
35. Borrero, N. V.; DeRatt L. G.; Abboud, K. A.; Aponick, A. “Tandem Gold-Catalyzed Dehydrative
Cyclization/Diels–Alder Reactions: Facile Access to Indolocarbazole Alkaloids”
Org. Lett., 2015, 17,1754. DOI
34. Paioti, P.H.S.; Aponick, A. “Progress in Au-Catalyzed Dehydrative Transformations of Unsaturated
Alcohols” Top. Curr. Chem. 2014, 357, 63. DOI
33. Paioti P. H. S.; Ketcham, J. M.; Aponick, A. “Controlling Regiochemistry in the Gold-Catalyzed
Synthesis of Unsaturated Spiroketals” Org. Lett., 2014, 16, 5320. DOI
32. Kahali, B.; Marquez, S. B.; Thompson, K. W.; Yu, J.; Gramling, S. J. B.; Lu, L.; Aponick, A.; Reisman,
D. “Flavonoids from each of the six structural groups reactivate BRM, a possible cofactor for thee
anticancer effects of flavonoids” Carcinogenesis 2014, 35, 2183. DOI
31. Cardoso, F. S. P.; Abboud, K. A.; Aponick, A. “Design, Preparation, and Implementation of an
Imidazole-Based Chiral Biaryl P,N-Ligand for Asymmetric Catalysis” J. Am. Chem. Soc. 2013,135,
14548. DOI
-Highlighted in Nature Chemistry: Nature Chemistry 2013, 5, 896.
-Highlighted in Synfacts: Synfacts 2014, 10, 40.
-Highlighted by Brown in his perspective on the state-of-the-art: J. Org. Chem. 2014,
79, 5391. DOI
30. Ketcham, J. M.; Cardoso, F. S. P.; Biannic, B.; Aponick, A. “Nitrogen Nucleophiles in Au-Catalyzed
Dehydrative Cyclization Reactions” Isr. J. Chem. 2013,53, 923. DOI
-Invited manuscript in thematic issue on gold catalysis.
29. Ghebreghiorgis, T.; Kirk, B. H.; Aponick, A.; Ess, D. H. “Multiple Mechanisms in Pd(II)-Catalyzed SN2'
Reactions of Allylic Alcohols” J. Org. Chem. 2013, 78, 7664. DOI
28. Palmes, J. A.; Paioti, P. H. S.; de Souza, L. P.; Aponick, A. “Pd(II)-Catalyzed Spiroketalization of
Ketoallylic Diols” Chem. Eur. J. 2013, 19, 11613. DOI
27. Cardoso, F. S. P.; Aponick, A. “1,2-Divinylethylene carbonate (mixture of DL- and meso-isomers)”
e-EROS 2013. DOI
26. Ketcham, J. M.; Aponick, A. “Synthesis of Saturated Heterocycles via Metal-catalyzed Allylic Alkylation
Reactions” Top. Heterocycl. Chem. 2013, 32, 157. DOI
25. Ketcham, J. M.; Biannic, B.; Aponick, A. “The Tandem Intermolecular Hydroalkoxylation/Claisen
Rearrangment” Chem. Commun. 2013, 49, 4157. DOI
- Invited Article for ChemComm 2013 Emerging Investigator Issue
- Highlighted by Echavarren in an article entitled “Towards the Ideal Synthesis
of Homoallylic Ketones” ChemCatChem 2015, 7, 228. DOI
24. Palmes, J. A.; Aponick, A. “Strategies for Spiroketal Synthesis Based on Transition-Metal Catalysis”
Synthesis 2012, 44, 3699. DOI
23. Borrero, N. V.; Aponick, A. “Total Synthesis of Acortatarin A using a Pd(II)-Catalyzed Spiroketalization
Strategy” J. Org. Chem. 2012, 77, 8410. DOI
22. Ghebreghiorgis, T.; Biannic, B.; Kirk, B. H.; Ess, D. H.; Aponick, A. “The Importance of Hydrogen
Bonding to Stereoselectivity and Catalyst Turnover in Gold-Catalyzed Cyclization of Monoallylic
Diols” J. Am. Chem. Soc. 2012, 134, 16307. DOI
21. Biannic, B.; Aponick, A. “Gold-Catalyzed Dehydrative Transformations of Unsaturated Alcohols”
Eur. J. Org. Chem. 2011, 6605. DOI
20. Biannic, B.; Ghebreghiorgis, T.; Aponick, A. “A comparative study of the Au-catalyzed cyclization of
hydroxy-substituted allylic alcohols and ethers” Beilstein J. Org. Chem. 2011, 7, 802. DOI
19. Chojnacka, K,; Santoro, S.; Awartani, R.; Richards, N. G. J.; Himo, F.; Aponick, A. “Synthetic Studies
on the Solanacol ABC Ring System by Cation-Initiated Cascade Cyclization: Implications for
Strigolactone Biosynthesis” Org. Biomol. Chem. 2011, 9, 5350. DOI
- Included in the Top 10 most accessed papers in June 2011
18. Aponick, A; Biannic, B.; “Chirality Transfer in Au-Catalyzed Cyclization Reactions of Monoallylic Diols:
Selective Access to Specific Enatiomers Based on Olefin Geometry” Org. Lett. 2011, 13, 1330. DOI
- Highlighted in Synfacts: Synfacts 2011, 5, 526.
17. Aponick, A; Biannic, B.; Jong, M. R. “A highly adaptable catalyst system for the synthesis of substituted
chromenes” Chem. Commun. 2010, 46, 6849. DOI
16. Aponick, A; Li, C.-Y.; Malinge, J.; Marques, E.F.; “An Extremely Facile Synthesis of Furans, Pyrroles,
and Thiopenes by the Dehydrative Cyclization of Propargyl Alcohols” Org. Lett., 2009, 11, 4624. DOI
- Highlighted in Synfacts: Synfacts 2010, 1, 93.
15. Aponick, A; Li, C.-Y.; Palmes, J. A.; “Au-catalyzed cyclization of Monopropargylic Triols: An Expedient
Synthesis of Monounsaturated Spiroketals.” Org. Lett., 2009, 11, 121. DOI
14. Aponick, A.; Biannic, B.; “Gold Catalyzed Dehydrative Cyclization of Allylic Diols”
Synthesis, 2008, 20, 3356. DOI
13. Aponick, A.; Dietz, A. L.; Pearson, W. H.; “2-(3-Pyrrolin-1-yl)-1,4-naphthoquinones: Photoactivated
Alkylating Agents” Eur. J. Org. Chem., 2008, 25. DOI
12. Aponick, A.; Li, C.-Y.; Biannic, B.; “Au-Catalyzed Cyclization of Monoallylic Diols”
Org. Lett., 2008, 10, 669. DOI
-Highlighted in Synfacts: Synfacts 2008, 4, 387.
11. Trost, B.M.; Aponick, A.; Stanzl, B.N. “A Convergent Pd-Catalyzed Asymmetric Allylic Alkylation of
dl- and meso-Divinylethylene Carbonate: Enantioselective Synthesis of (+)-Australine Hydrochloride”
Chem.- Eur. J. 2007, 13, 9547. DOI
10. Trost, B.M.; Machacek, M.R.; Aponick, A. “Predicting the Stereochemistry of DPPBA Based Palladium-
Catalyzed Asymmetric Allylic Alkylation Reactions: A Working Model”
Acc. Chem. Res., 2006, 39, 747. DOI
9. Pearson, W.H.; Aponick, A.; Dietz, A.L. “Synthesis of N,N-Bis(3-butenyl)amines from 2-Azaallyl
Dication Synthetic Equivalents and Conversion to 2,3,6,7-Tetrahydroazepines by
Ring-Closing
Metathesis” J. Org. Chem. 2006, 71, 3533. DOI
8. Pearson, W.H.; Aponick, A. “Formal Synthesis of Aspidosperma Alkaloids via the Intramolecular [3+2]
Cycloaddition of 2-Azapentadienyllithiums” Org. Lett. 2006, 8, 1661. DOI
7. Trost, B.M.; Aponick, A. “Palladium-Catalyzed Asymmetric Allylic Alkyation of meso- and dl-1,2-
Divinylethylene Carbonate” J. Am. Chem. Soc. 2006, 128, 3931. DOI
6. Aponick, A.; Buzdygon, R.S.; Tomko, R.J.; Fazal, A.N.; Shughart, E.L.; McMaster, D.M.; Myers, M.C.;
Pitcock, W.H.; Wigal, C.T. “Regioselective Organocadmium Alkylations of Substituted Quinones”
J. Org. Chem. 2002, 67, 242. DOI
5. Pearson, W.H.; Stevens, E.P.; Aponick, A. “Studies on the Asymmetric Cycloaddition of 2-Azaallyl
Anions with Alkenes” Tetrahedron Lett. 2001, 42, 7361. DOI
4. Pearson, W.H.; Aponick, A. “Double Allylation Reactions of (2-Azaallyl)stannanes: Synthesis of
N,N-Bis(3-butenyl)amines and Their Conversion to 2,3,6,7-Tetrahydroazepines via Ring-Closing
Metathesis” Org. Lett. 2001, 3, 1327. DOI
3. Aponick, A.; McKinley, J.; Raber, J.C.; Wigal, C.T. “Quinone Alkylation Using Organocadmium
Reagents: A General Synthesis of Quinols” J. Org. Chem. 1998, 63, 2676. DOI
2. Aponick, A.; Marchozzi, E.; Johnston, C.; Wigal, C.T. “Determining the Authenticity of Gemstones
Using Raman Spectroscopy” J. Chem. Ed. 1998, 75, 465. DOI
1. McKinley, J.; Aponick, A.; Raber, J.C.; Fritz, C.; Montgomery, D.; Wigal, C.T. “Reactions of
Alkyllithium and Grignard Reagents with Benzoquinone: Evidence for an Electron-Transfer
Mechanism” J. Org. Chem. 1997, 62, 4874. DOI
